Shiaulou Yuan, PhD
Assistant Professor of Medicine
Principal Investigator

Dr. Shiaulou Yuan is an Assistant Professor of Medicine at Massachusetts General Hospital and Harvard Medical School. Dr. Yuan received his undergraduate degree in molecular cell biology from University of California, Berkeley in 2004 under Dr. Athanasios Theologis. He completed his Ph.D. in genetics from Yale University in 2011 with Dr. Zhaoxia Sun. Dr. Yuan performed his postdoctoral training in cardiovascular biology and developmental biology with Dr. Martina Brueckner at Yale School of Medicine. He received additional postdoctoral training in light sheet microscopy, laser nanosurgery techniques, and biophysical approaches with Dr. Joe Howard at Yale University and Dr. Scott Fraser at University of Southern California. In 2018, he started his own independent laboratory in the Cardiovascular Research Center at Massachusetts General Hospital and Harvard Medical School. Dr. Yuan’s research focuses on elucidating the cellular and molecular mechanisms that shape the developing heart, and in particular, the function of cilia in this process.

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Mohammed Mahamdeh, PhD
Instructor of Medicine
Assistant Director of Molecular Imaging Center

Dr. Mohammed Mahamdeh is an Instructor of Medicine at Massachusetts General Hospital and Harvard Medical School. Dr. Mahamdeh received his undergraduate degree in applied physics from Jordan University of Science and Technology in 2000. He completed his master’s degree in biological physics from KTH Royal Institute of Technology in 2007 with Dr. Hjalmar Brismar. Dr. Mahamdeh received his PhD in physics from TU Dresden in 2011 under Dr. Erik Schäffer. He completed his postdoctoral training in biophysics and microtubule biology with Dr. Joe Howard at Yale University. In 2018, Dr. Mahamdeh was recruited to the Yuan lab to develop cutting-edge microscopy techniques and investigate ciliary biomechanics. In 2020, Dr. Mahamdeh was appointed as an assistant director in the Molecular Imaging Center at MGH/HMS.

Lydia Djenoune, PhD
Postdoctoral Research Fellow

Dr. Lydia Djenoune is a Postdoctoral Fellow in the Yuan lab. After completing her Master of Genetics from Paris Diderot University, she received her PhD from the French National Museum of Natural History under the mentorships of Dr. Claire Wyart and Prof. Hervé Tostivint studying the molecular and morphological heterogeneity of the cerebrospinal fluid-contacting neurons and the role of the polycystin channel Pkd2l1 in zebrafish spinal cord. For her postdoctoral training, she first joined the group of Prof. Iain Drummond at The Massachusetts General Hospital to probe the role of calcium signaling in kidney glomerular morphogenesis. In the Yuan lab, Lydia is investigating the role of intra-ciliary calcium and mechanosensation in cardiac left-right development. 

Amelie Brugger, BS
Graduate Student

Amelie Brugger is a graduate student in the Yuan lab. Amelie received her undergraduate degree in biology from Hohenheim University in 2018